Bioanalytical Services
The Bioanalytical Services Department offers scientific excellence, uncompromised quality and unbeatable timelines to meet and exceed client needs.
Our GLP-compliant bioanalytical Canadian facility, located in Laval (Quebec, Canada), is 20,000 sq feet (1850 sq metres), with 24 LC-MS/MS systems (19 API3000 & 5 API5000 operating 24/7), 5 LC-MS, 9 UV detectors and 5 fluorescence detectors. It is fully equipped with a dedicated method development group and multiple state-of-the-art equipment, ensuring a straightforward and compliant submission for any country.
Our expertise, combined with our state-of-the-art instrumentation, allows us to achieve:
- Extremely low LLOQ
- Large dynamic ranges
- Analysis of multiple metabolites
- Analysis from various matrices and species
- Quick method development using strict criteria
- Successful method transfer or adaptation
We are also working on methods using new and/or high throughput technologies, such as the Dried Blood Spot analysis (DBS). Through our expertise we can overcome challenges like potential stability issues and matrix effects. One of our major focuses is to develop methods that are free of interference from metabolites.
Our Bioanalysis Group is responsible for method validation and study sample analysis, with:
- Experience working with different matrices and species
- Experience with complex multi-sites and Phase IIa/III studies
- Highly trained employees on GLP and international regulations
- Flexibility and quick timelines using on-going Quality Assurance
We perform assays on almost 400,000 samples per year, many for multiple analytes and comprising parent drug and several metabolites in one single assay. Sample analysis is performed for projects carried out in our own clinics as well as for external projects (from preclinical to Phase I-IV).
