We offer streamlined acute toxicity studies designed to help predict likely target organ systems and help with dose selection for initial repeated dose toxicity tests.
Our acute toxicity studies are designed to evaluate the adverse effects that occur either immediately or at a short time interval — within 24 hours — after a single or multiple administration of a substance. Adverse effects are any effects that produce functional impairments in organs and/or biochemical lesions, which could alter the functioning of the organism in general or individual organs. As such, our study designs typically focus on evaluating these endpoints to thoroughly assess the short term effect of your test article.
Our deep expertise and capabilities in a broad range of therapeutic areas encompasses preclinical and early clinical studies for both small molecules and biologics. We can manage your entire program, as well as provide support research services and bioanalytical expertise.
Please see Therapeutic Areas for a fuller discussion of our capabilities and expertise.