Scientific Publications
The Altascientist
THE ALTASCIENTIST, ISSUE NO. 8
Facing bioanalytical challenges when evaluating the immunogenicity profile of protein-based therapeutic drugs
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SCIENTIFIC PUBLICATIONS
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Scientific Publication
Development of an Affinity Capture - LC-MS/MS Assay for the Quantitation of Adalimumab in Human Plasma using BioBA Sample Preparation Kit
By: Josée Michon1, Jean-François Dupuis1, Kevork Mekhssian1, Ian Moore2, Anahita Keyhani1
1. Altasciences Clinical Research, Laval, Québec, Canada
2. SCIEX, Concord, Ontario, Canada
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Scientific Publication
Stability Evaluation of Captopril in Human Blood by LC-MS/MS
By: Eugénie-Raphaëlle Bérubé, Milton Furtado and Anahita Keyhani
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Scientific Publication
The Application of Research Grade MetabolitePilot™ Software for the Determination of Exenatide Catabolites using HRAM with SWATH Acquisition
By:Jeff Plomley1, Yi Zhang2, Eva Duchoslav2, Daniel Villeneuve1, Kevork Mekhssian1 and Anahita Keyhani1.
1. Altasciences, Laval, Quebec, Canada
2. SCIEX, Concord, Ontario, Canada
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Scientific Publication
Large Molecule Application of Volumetric Absorptive Microsampling for Single-Rodent PK Profiling of Exenatide Determined by LC-MRM
By:Jeff Plomley1, Daniel Villeneuve1, Mingluan Chen1 Kevork Mekhssian1, Nikolay Youhnovski1, Olivier Didur2, William Ruddock2 and Anahita Keyhani1.
1. Altasciences, Laval, Quebec, Canada
2. ITR Laboratories Canada, Montreal, Quebec, Canada
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Scientific Publication
Development of a Multi-Peptide Immunocapture – LC-MS/MS Assay for the Quantitation of a PEGylated Therapeutic in Rat and Dog Plasma
By:Kevork Mekhssian1, Jean-François Dupuis1, Olivier Didur2, William Ruddock2 and Anahita Keyhani1.
1. Altasciences, Laval, Quebec, Canada
2. ITR Laboratories Canada, Montreal, Quebec, Canada
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Scientific Publication
A Novel Strategy for the In-Process Stabilization of N-Oxide Metabolites in Hemolyzed Plasma Determined by LC-MS/MS
By:Richard Lavallée, Georges Koudssi, Milton Furtado and Anahita Keyhani.
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Scientific Publication
Biotherapeutic Application of Volumetric Absorptive Microsampling for Single-Rodent PK Profiling of Exenatide Determined by LC-MRM
By: Jeff Plomley1, Daniel Villeneuve1, Mingluan Chen1, Kevork Mekhssian1, Olivier Didur2, William Ruddock2, Anahita Keyhani1.
1. Altasciences, Laval, Quebec, Canada
2. ITR Laboratories Canada, Montreal, Quebec, Canada