Quantification of Endogenous Biomarkers in Biological Matrices
The quantitation of endogenous compounds in biological methods requires reliable validated assays. Using the required surrogate reference standard (in most cases a recombinant reference standard that allows the relative quantitation of the endogenous analyte) can be challenging. To assess the suitability of the reference standard you need to demonstrate acceptable parallelism between the endogenous analyte and the calibration curve upon multiple dilutions. Our team can help!
Download this insert to find out more about the approaches used by Altasciences to validate and monitor assay performance.
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You may also be interested in the following:
- Webinar: Certificate of Analysis Essentials for Regulated Bioanalysis
- Webinar: Selectivity, Selectivity, Selectivity — a New Dimension by Differential Mobility Spectrometry
- Webpage: Bioanalytical Assay List
- Webpage: Translational Biomarkers
Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining solutions, whether a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services from lead candidate selection to clinical proof of concept, and beyond.