Preclinical Research

  • Preclinical Research
  • Answers to your questions on the development of biologics and biosimilars

     

    Renowned for our full-service offering, we often get asked — how does Altasciences manage the development process for biologics and biosimilars so seamlessly from the required preclinical studies to first-in-human trials?

    When and How to Use Thromboelastography (TEG) in Preclinical Studies

    Thromboelastography (TEG) is often used to measure clot strength, diagnose and quantify fibrinolysis, as well as help diagnose platelet dysfunction and hypercoagulability. TEG analysis is utilized in preclinical studies targeting bleeding disorders and platelet dysfunction, and can add valuable information in drug development focused on hematology and coagulation.

    Want to know more? Our scientific poster discusses the various benefits, challenges, and methods associated with the use of TEG in preclinical studies, including a case study.

    View the Poster and Case Study

    Learn more on Altasciences' Preclinical Studies

    Use of Thromboelastography (TEG) in Preclinical Studies

    Development of an IL-31-Induced Pruritus Model in Cynomolgus Monkeys

    Effect of Housing on Stress-Related Parameters in NHPs

    Detection of Peripheral Blood Foxp3+ Regulatory T Cell Population in a Preclinical Setting

    Translatability of Non-Human Primate Cytokine Data to In-Life Parameters in Nonclinical

    A Multi-Peptide Hybrid LC-MS/MS Assay for the Determination of CTI-1601 in Monkey Tissues Provides Insight into its Disposition and Processing

    Assessing an animal welfare program

    When choosing an outsourcing partner for your nonclinical studies, it is imperative to evaluate the strength of a contract research organization's animal welfare program. Since animal welfare is the cornerstone for achieving high quality scientific results, understanding the components of a successful program can guide you in your assessment.

    Does your CRO have what it takes?

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