Preclinical Services

Altasciences offers a full range of in vivo GLP and non-GLP preclinical evaluation studies in multiple species to thoroughly assess the safety of our clients’ molecules. Our solution offering includes IND/NDA-enabling toxicology, safety pharmacology and laboratory services that meet global regulatory requirements for both small and large molecules. Altasciences’ team of scientists and technicians have been conducting toxicology studies for over 25 years, and are committed to working as an extension of our clients, going above and beyond to meet increasingly complex needs.

Pre-clinical Services

Toxicology and Laboratory Services
  • General Toxicology (acute, sub-chronic, chronic)
  • Safety Pharmacology (CNS, respiratory, cardiovascular)
  • Reproductive Toxicology
  • Immunotoxicology/Immune Function
  • Pharmacokinetics (PK)
  • Pharmacodynamics (PD)
  • Non-GLP Lead Optimization
Comprehensive Full-Service Offering

Altasciences offers a full support service model to complement our preclinical offering to best meet your needs:

  • Protocol Development
  • Project Management
  • Analytical Chemistry
  • Bioanalysis(small and large molecules)
  • Toxicokinetics
  • Anatomic Pathology
  • Clinical Pathology
  • Reporting
  • SEND
  • Archiving
  • Scientific, Regulatory and Strategic Guidance
SPECIES
  • Rat
  • Mouse
  • Dog
  • NHP
  • Rabbit
  • Guinea pig
  • Mini Pig
  • Swine
ROUTES OF ADMINISTRATION
  • Oral (gavage, diet, capsule)
  • Parenteral (intravenous, subcutaneous, intramuscular, intraperitoneal, intrathecal and intra-articular)
  • Ocular
  • Intranasal
  • Topical
  • Intravaginal
  • Clinical Pathology
  • Rectal
Overview of Our Preclinical Facility

Altasciences’ preclinical facility is designed to provide efficient and standardized workflows to ensure consistency in practices and uniformity in results. With industry-leading start times and competitive reporting timelines that include an on-time reporting rate of 98%, our goal is to exceed all your expectations.

  • GLP and non-GLP studies
  • Expertise with both rodent and non-rodent species
  • Experience in small and large molecule safety testing
  • 210,000-sq.-ft. purpose-built facility with over 250 team members
    • 140 custom-designed animal rooms, including European housing
    • Barrier facilities for NHPs, dogs, mini pigs, and rodents
    • AAALAC accredited, USDA registered, OLAW Assurance, BSL-2
    • Client-dedicated NHP colonies
    • FDA inspected
    • Archive facility and services on site
  • Conduct hundreds of NHP studies per year