Bioanalysis
Seamless Bioanalytical Transition from Preclinical to Clinical, and Beyond
Seamless Bioanalytical Transition
Altasciences’ scientists move in unison with you, collaboratively, accurately, and efficiently, from preclinical to clinical, and beyond. Our team of over 260 bioanalytical scientific veterans is strategically located across North America, and has experience with a wide spectrum of biological matrices in both animal and humans.
Driven by your assay requirements, our program support includes LC-MS/MS, LBA OR HYBRID LBA/LC-MS/MS ASSAY platforms for:
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Have 5 minutes? You may also be interested in the following:
- Assay List — Over 685 Assays covering 650 Molecules
- The Altascientist — Validation of Immunogenicity Assays
- Webinar — Development of a Cell-Based Assay for Dual Purposes: to Support Drug Potency and Immunogenicity Characterization
Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining drug development solutions, whether for a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services.
Flow Cytometry — Integrated for Efficiency
Altasciences’ preclinical and clinical sites share the same validation of instrumentation and panels to ensure a smooth transition. Our flow cytometry labs are located near our clinical pharmacology units, for rapid turnaround between sample collection and analysis.
Preclinical Applications
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Clinical Applications
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Let’s schedule a conversation to review your program needs.
You may also be interested in the following:
- Four Reasons to Choose Altasciences as Your Flow Cytometry Partner
- Flow Cytometry Capabilities
- Comprehensive Clinical Trial Services
- Preclinical Services
Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining drug development solutions, whether for a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services from lead candidate selection to clinical proof of concept, and beyond.
One Integrated Solution for Meeting Your Preclinical to Clinical Drug Development Needs
Multiplexed Cytokine Comparison Across Two Species Dosed with the Same Drug
Detection of Plasma Cells and their Precursors in Bone Marrow and Peripheral Blood
Evaluating Cytokine Data in Nonhuman Primate Safety Assessment Studies: A Correlation to Toxicity Outcomes
COMPLIMENTARY WEBINAR — Cell-Based Assays
Key Considerations for Developing
Cell-Based Assays
In this complimentary webinar, Dr. Danielle Salha, Senior Director, Immunochemistry and Immunology, Ligand Binding Assays, discusses key parameters to consider during method development to support drug potency and immunogenicity characterization.
Topics covered:
- Reducing development timelines and management of critical reagents
- Important parameters to consider for NAb method development and for the development of potency assays
- Management of critical reagents to support long-term clinical studies
- Advantages of using the same method for both immunogenicity assessment and product characterization
- Challenges that may be encountered when developing cell-based assays
You may also be interested in the following:
- Ligand Binding Capabilities
- Bioanalytical Assay List
- The Altascientist — Validation of Immunogenicity Assays
Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining drug development solutions, whether for a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services from lead candidate selection to clinical proof of concept, and beyond.
ASOs — Expert Interviews, Case Studies, and More!
It’s All About ASOs!
Antisense oligonucleotides (ASOs) offer an exciting pathway to targeting the source of a disease’s pathogenesis. In this e-book, we take a deep dive into the bioanalytical development for the analysis of ASOs.
Topics covered:
- Benefits and challenges of novel ASO bioanalytical approaches.
- Case studies examining how best to align a bioanalytical technique with the goals of a particular ASO drug development program.
Speak with an expert.
Have 5 minutes? Take a look at these:
- Comprehensive Bioanalytical Services
- Altasciences' Proprietary Bioanalytical Assay List
- Three Laboratories – One Vision (PODCAST)
Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining drug development solutions, whether for a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services from lead candidate selection to clinical proof of concept, and beyond.
A Solution to Drive Your Drug Development Forward
Nonclinical and Clinical Research Services — Phase I to IV
Whether you are looking for a full-service solution or a stand-alone offering, Altasciences will help guide you along the way. We are accustomed to managing complex projects with different partners, and have robust communication and operational processes in place to ensure efficient integration.
We offer a range of services for early phase and late phase studies, including:
- Program Management
- Clinical Monitoring
- Scientific Publication Development and Review
- Protocol Development and Medical Writing
- PK/PD Analysis and Interpretation
- Data Management
- Biostatistics and Statistical Analysis
- Support Services for Non-Clinical Studies
Have 5 minutes? You may be interested in this:
- Clinical Trial Services
- Podcast — Choosing the Right CRO for Your Clinical Trial Monitoring
- Blog — Five Things You Need to Know About Partnering with an Integrated CRO/CDMO
Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining drug development solutions, whether for a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services from lead candidate selection to clinical proof of concept, and beyond.
How to Maximize Drug Development Success of Biologics
Combining Trial Conduct and Bioanalysis for Success
Combining Phase I trial conduct of biologics and bioanalysis is critical for successful drug development. Clinical development relies heavily on bioanalytical experts to generate critical data to understand pharmacokinetics and pharmacodynamics.
Here are just some of the benefits of working with Altasciences:
- Timed interim sample analysis for dose escalation decisions
- Rapid turnaround of PK/PD analysis between cohorts
- Biomarker development and validation for exploratory or primary endpoints
- Proximity flow cytometry
- Centralized scheduling between clinic and lab
- Ability to easily switch or combine platforms which are sensitive, have high throughput, and demonstrate exquisite specificity
Watch this complimentary webinar to see how you can overcome challenges throughout all phases of drug development.
Have 5 minutes? Take a look at these:
- How Is Partnering with Altasciences for Your First-in-Human Clinical Trials Different?
- Microsampling in Drug Development
- Validated Bioanalytical Assay List
Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining solutions, whether for a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services from lead candidate selection to clinical proof of concept, and beyond.