Bioanalysis
Inside The Altascientist: The Benefits of PCR for Your Gene Therapy Programs
The gene therapy landscape continues to accelerate in preclinical and clinical research, with programs constantly in development for targeted, personalized medicines. The goal is to safely incorporate genetic alterations to restore and repair the proteins of missing and/or faulty genes.
Strategies for Safe and Timely Shipments
Your Samples Are in Good Hands With Us!
From regulatory precision to preserving sample integrity, shipments can be challenging. Let us navigate and mitigate these challenges for you with a team of logistical experts to:
• Streamline regulatory compliance through optimized documentation practices.
• Prioritize secure, temperature-controlled shipments with reliable couriers.
• Ensure your samples maintain their integrity with temperature monitoring, robust packaging, and contingency planning.
• Our tailored concierge-style sample shipping ensures your test materials reach the correct destination safely and on time.
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Fact Sheets
Sample Kits
Bioanalytical Services
Webpages
Bioanalytical Services
Clinical Services
Preclinical Services
How Mitra® Vams® Microsampling Device Redefines Sample Collection
From Concept to Application
Delve into the fascinating evolution and revolutionary advancements of the Mitra Vams microsampling device and its applications within life sciences with Dr. James Rudge, Microsampling Technical Director at Neoteryx, and Jeff Plomley, Scientific Director at Altasciences.
Listen now!
Speak with one of our bioanalytical experts today.
Related resources that may interest you:
Microsampling Podcast Series:
Episode 1: When Small Steps Lead to Big Outcomes
Episode 2: Coupling Hybridization LC-MS Workflows With Microsampling
The Altascientist: Microsampling in Drug Development
Webpage: Microsampling in Early Drug Development
Three Platforms Used to Monitor Cytokines and the Complement System
Monitoring both cytokines and complement factors in drug development has become increasingly important, as the movement toward personalized treatments for cancers and genetic diseases has spurred research and development into biologics, vaccines, and small molecules that can have unintended consequences due to their immunomodulatory effects.
Q&A With Dr. Norbert Makori and Pierre Jolicoeur: The Benefits of Combining Preclinical and Bioanalytical Solutions for Your Gene Therapy Studies
Recent advances in gene therapy have allowed for diseases to be approached differently. Gene therapy was first discovered in the 1960s, but only gained commercial interest in the 1980s. It wasn’t until 1990 that the first successful gene therapy treatment on a patient transpired.
Laboratory Sciences Resource Library
A Wealth of Information at Your Fingertips
Explore Altasciences’ bioanalytical resources for comprehensive solutions tailored to your specific requirements. Altasciences’ bioanalytical team specializes in assay development from discovery to preclinical to Phase IV for both small and large molecules.
The Altascientist—A Scientific Journal
The Evolution and Advancement of Liquid Chromatography-Mass Spectrometry in Drug Development. Read or listen to the issue>>>
Validation of Immunogenicity Assays. Read or listen to the issue>>>
Microsampling in Drug Development. Read or listen to the issue>>>
eBook
Key Biomarkers of Immunomodulation. Read or listen to the eBook>>>
Webinars
Uses of Digital Droplet PCR (ddPCR) in Preclinical Research. Watch the webinar>>>
Development of a Cell-Based Assay for Dual Purposes: to Support Drug Potency and Characterize Immunogenicity. Watch the webinar>>>
Speak with an expert today to learn more about our bioanalytical solution.
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Bioanalytical Services
Assay List
Supporting the Future of Immunomodulatory Drugs
Achieve Critical Milestones in Your Drug Development Program
At Altasciences, we specialize in diverse immunomodulators, including proteins, oligonucleotides, biologics, bispecific antibodies, and gene therapy.
Our evaluations count on essential biomarkers, like cytokines, complement factors, immune cell subtyping, and functional measurements.
Rely on us for:
- precise drug quantitation and biomarker assessment;
- state-of-the-art bioanalytical platforms to monitor multiple aspects of immunomodulation in various species;
- bioanalytical teams with relevant experience handling pathogens and working with infectious samples for your vaccine development programs; and
- labs equipped with containment Level 2 (CL2) areas for handling pathogens within the Risk Group 2.
Need more guidance? Send us a message.
You may also be interested in the below resources:
Fact Sheet: Immunogenicity Testing
eBook: Key Biomarkers of Immunomodulation
Webpage: Bioanalytical Platforms
Accelerating Decentralized Clinical Trials with Precise ASO Analysis
In this poster presentation, Dr. Mingluan Chen discusses the first successful application leveraging the Capitainer® qDBS device, for the quantitative bioanalysis of Fomivirsen ASO and its 5’ n-1 metabolite from dried blood micro samples using a hybridization LC-MS/MS workflow.
The ability to quantify ASOs accurately and efficiently in dried blood samples means critical patient populations may be more readily accessible for decentralized clinical trials. This can lead to faster, more efficient research and improved patient outcomes.
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Webpages:
Research Articles:
Accurate Quantification of ASOs in Mouse Serum Using Microsampling LC-MS/MS
Poster Presentations:
Application of Mitra® Microsampling for the Quantitative Bioanalysis of ASOs