Preclinical Research
Scratching the Surface of Nonclinical Dermal Testing
Altasciences Simplifies Dermal Safety Testing for You
To bring your molecule from discovery to clinical proof-of-concept and beyond, Altasciences' team of toxicologists and technicians provides a wide range of dermal services. We work with you to develop new or validate existing dermal models, and perform GLP and non-GLP toxicology studies to support both 505(b)(2) and new chemical entity regulatory filings.
When you partner with Altasciences, you benefit from a CRO who can:
• Conduct safety assessments on both small and large molecules
• Design and conduct standard and specialty dermal toxicology studies that support your FDA filings
• Assess topical therapies using miniature swine and nonhuman primates
View our eBook on the topic, or consult with one of our experts to discuss your study needs.
You may also be interested in these related resources:
• Webpage: Full Range of Preclinical Drug Development Solutions
• Fact Sheet: Preclinical Services Capabilities
• The Altascientist: Planning Your Preclinical Assessment
Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining drug development solutions, whether for a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services from lead candidate selection to clinical proof of concept, and beyond.
Altasciences' Proactive Drug Development Solution: Large Molecules
How Miniature Swine Models Are Revolutionizing Preclinical Research
More Models, More Options
The miniature swine has emerged as a viable non-rodent alternative for nonclinical studies. Our team has extensive experience with miniature swine in several therapeutic areas, including dermal, cardiovascular, metabolic diseases, inflammation, and wound healing.
Want to explore this promising option further?
DISCOVER MORE
You may also be interested in the following:
Webinars:
- Miniature Swine Model Selection Criteria for Toxicology and Pharmacology Studies
- Downsized Miniature Swine: A New Spin on the Oldest Model
Interview: Selecting Miniature Swine Models for Your Toxicology Study
Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining drug development solutions, whether for a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services.
What Makes Our Pathologists Unique?
A Chat With Dr. Wendell Davis
Altasciences’ team of in-house pathologists has expertise with different test articles, drug modalities, and species. With close to 30 years of experience each, our pathologists can support your toxicology studies and help to set safety margins for your clinical trials.
Watch Dr. Wendell Davis, Vice President of Pathology, explain what makes Altasciences' pathology team unique.
Learn more about our pathology capabilities:
Podcast: Digital Pathology―Establishing the Capability
Press Release: Altasciences Selects Proscia to Accelerate the Development of Life-Saving Drugs
A Changing Paradigm in Nonclinical Studies
In this issue of The Altascientist, we cover the changing paradigm for non-rodent species selection in nonclinical safety studies, and how the miniature swine is a viable option in small and large molecule studies.
We discuss:
Miniature swine size considerations
Species selection criteria and processes
Four case studies
DOWNLOAD NOW
You may also be interested in the following:
Webpage: Miniature Swine in Nonclinical Studies
Webinar: Downsized Miniature Swine: A New Spin on the Oldest Model
Educational Video: How Do I Select the Right Species for My Toxicology Program?
A Virtual Tour You Won't Want to Miss!
A Virtual Tour You Won't Want to Miss!
Step inside our nonclinical facility in Scranton, PA, with this virtual tour. Discover how our expertise in efficacy pharmacology, ophthalmology, and carcinogenicity, to name a few, can support your nonclinical study needs.
Highlights include:
- 40 animal rooms
- Capacity to house ~140 NHPs, ~350 canines, ~350 swine, and ~6,500 rodents
- On-site archive facility (1,840 sq. ft.)
- Accreditations/Certifications:
- AAALAC accredited
- USDA registered
- EPA inspected
REQUEST A TOUR NOW
Speak with one of our experts to learn more about our service offering.
Have five minutes? Take a look at these:
Webpages: Preclinical Testing Facilities
Fact Sheet: Preclinical Drug Development
Webinar: Navigating the Challenges of Early Drug Development
Development of a Flow Cytometry Phospho-STAT5 Assay in Nonhuman Primate T Cells
Strategies for Reducing the Number of Animals in Toxicity Testing: A Comparative Approach for Rodent and Large Animal Studies