Preclinical Research

  • Preclinical Research
  • Sinclair Nanopig™: From Multi-Omics Characterization to Toxicology Validation

    Tissue Biopsy Collections in Nonhuman Primates During Toxicology Studies

    28-Day Intranasal Toxicity Study of MMS019 in Sprague Dawley Rats and Dogs

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    Recent advances in gene therapy have allowed for diseases to be approached differently. Gene therapy was first discovered in the 1960s, but only gained commercial interest in the 1980s. It wasn’t until 1990 that the first successful gene therapy treatment on a patient transpired.

    Understanding the effects of a drug, and how it interacts with the body, and vice versa, is critical to ensure it is safe for human use. This is where pharmacokinetic (PK), pharmacodynamic (PD), and toxicokinetic (TK) analyses step in.

    Proactive Drug Development for Large Molecules

    Introducing Philippine-Origin Cynomolgus Macaque As a Research Model

    Understanding Species Variation in the Occurrence of Spontaneous Background Eye Lesions

    Comparison of Cardiovascular and Respiratory Parameters in Three Strains of Research Pigs

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